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Easily convert video and audio between popular HD formats, such as MP4 and MP3, including 4K/UltraHD, Apple HD.Pyridoxine (vitamin B6) deficiency
Pyridoxine (vitamin B6) deficiency, a type of B vitamin deficiency, results in seizures, lethargy, and other neurological symptoms. Pyridoxine is required for the metabolism of numerous neurotransmitters and normal function of brain cells. Prolonged pyridoxine deficiency causes generalized seizures, and the deficiency is often diagnosed based on history and physical examination. In addition to symptoms similar to other types of vitamin deficiencies, pyridoxine deficiency can lead to the encephalopathic form of autism.
Signs and symptoms
Seizures, lethargy, and coma may occur in pyridoxine deficiency. Seizures are common, and are commonly the first symptom of pyridoxine deficiency. The patient may have seizures that are more likely to occur in the evening or at night, in addition to a general increase in seizure activity as the deficiency becomes more severe.
Pyridoxine is typically considered the most important B6 vitamin in the brain because about 95% of its endogenous syntheses comes from the pyridoxal phosphate form and its formation is tightly regulated.
Signs of vitamin B6 deficiency may be asymptomatic and can only be diagnosed through laboratory testing.
The condition is present from all causes of B6 deficiency. B6 deficiency may occur in a number of diseases that affect the digestive system including celiac disease. Increased need for B6 may occur from increased synthesis of protein in the liver or gut, which does not occur in other organs.
Threonine, the amino acid that creates pyridoxine is derived from three amino acids: as